Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons

Metabolite profiling is an important tool that may better capture the multiple features of neurodegeneration. With the considerable parallels between mouse and human metabolism, the use of metabolomics in mouse models with neurodegenerative pathology provides mechanistic insight and ready translatio...

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Udgivet i:Sci Rep
Main Authors: Geiszler, Philippine C., Ugun-Klusek, Aslihan, Lawler, Karen, Pardon, Marie-Christine, Yuchun, Ding, Bai, Li, Daykin, Clare A., Auer, Dorothee P., Bedford, Lynn
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859111/
https://ncbi.nlm.nih.gov/pubmed/29555943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23155-2
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