Genomic and Proteomic Resolution of Heterochromatin and its Restriction of Alternate Fate Genes

Heterochromatin is integral to cell identity maintenance by impeding the activation of genes for alternate cell fates. Heterochromatic regions are associated with histone 3 lysine 9 trimethylation (H3K9me3) or H3K27me3, but these modifications are also found in euchromatic regions that permit transc...

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Udgivet i:Mol Cell
Main Authors: Becker, Justin S., McCarthy, Ryan L., Sidoli, Simone, Donahue, Greg, Kaeding, Kelsey E., He, Zhiying, Lin, Shu, Garcia, Benjamin A., Zaret, Kenneth S.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858919/
https://ncbi.nlm.nih.gov/pubmed/29272703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.11.030
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