Long-Term Caloric Restriction Improves Cardiac Function, Remodeling, Adrenergic Responsiveness and Sympathetic Innervation in a Model of Post-Ischemic Heart Failure

BACKGROUND: Caloric restriction (CR) has been described to have cardioprotective effects and improve functional outcomes in animal models and humans. Chronic ischemic heart failure (HF) is associated with reduced cardiac sympathetic innervation, dysfunctional β-adrenergic receptor (β-AR) signaling a...

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Publicat a:Circ Heart Fail
Autors principals: de Lucia, Claudio, Gambino, Giuseppina, Petraglia, Laura, Elia, Andrea, Komici, Klara, Femminella, Grazia Daniela, D’Amico, Maria Loreta, Formisano, Roberto, Borghetti, Giulia, Liccardo, Daniela, Nolano, Maria, Houser, Steven R., Leosco, Dario, Ferrara, Nicola, Koch, Walter J., Rengo, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858906/
https://ncbi.nlm.nih.gov/pubmed/29535114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.117.004153
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