Shikonin induces mitochondria-mediated apoptosis and attenuates epithelial-mesenchymal transition in cisplatin-resistant human ovarian cancer cells

Cisplatin-based chemotherapy often results in the development of chemoresistance when used to treat ovarian cancer, which is difficult to overcome. The present study investigated the cytotoxic and anti-migratory effects of shikonin, a naphthoquinone compound, on cisplatin-resistant human ovarian can...

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Vydáno v:Oncol Lett
Hlavní autoři: Shilnikova, Kristina, Piao, Mei Jing, Kang, Kyoung Ah, Ryu, Yea Seong, Park, Jeong Eon, Hyun, Yu Jae, Zhen, Ao Xuan, Jeong, Yong Joo, Jung, Uhee, Kim, In Gyu, Hyun, Jin Won
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
Témata:
Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5858079/
https://ncbi.nlm.nih.gov/pubmed/29563994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8065
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