Purine nucleotide metabolism regulates expression of the human immune ligand MICA

Expression of the cell-surface glycoprotein MHC class I polypeptide-related sequence A (MICA) is induced in dangerous, abnormal, or “stressed” cells, including cancer cells, virus-infected cells, and rapidly proliferating cells. MICA is recognized by the activating immune cell receptor natural kille...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: McCarthy, Michael T., Moncayo, Gerard, Hiron, Thomas K., Jakobsen, Niels A., Valli, Alessandro, Soga, Tomoyoshi, Adam, Julie, O'Callaghan, Christopher A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857976/
https://ncbi.nlm.nih.gov/pubmed/29279329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.809459
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