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Local uncaging of caged Ca(2+) reveals distribution of Ca(2+)-activated Cl(−) channels in pancreatic acinar cells

In exocrine acinar cells, Ca(2+)-activated Cl(−) channels in the apical membrane are essential for fluid secretion, but it is unclear whether such channels are important for Cl(−) uptake at the base. Whole-cell current recording, combined with local uncaging of caged Ca(2+), was used to reveal the C...

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Autors principals: Park, Myoung Kyu, Lomax, Richard B., Tepikin, Alexei V., Petersen, Ole H.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC58579/
https://ncbi.nlm.nih.gov/pubmed/11535807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181353798
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