Transformation of local Ca(2+) spikes to global Ca(2+) transients: the combinatorial roles of multiple Ca(2+) releasing messengers

In pancreatic acinar cells, low, threshold concentrations of acetylcholine (ACh) or cholecystokinin (CCK) induce repetitive local cytosolic Ca(2+) spikes in the apical pole, while higher concentrations elicit global signals. We have investigated the process that transforms local Ca(2+) spikes to glo...

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Detalles Bibliográficos

Publicado en:	EMBO J
Principais autores:	Cancela, Jose M., Van Coppenolle, Fabien, Galione, Antony, Tepikin, Alexei V., Petersen, Ole H.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Publishing Group 2002
Assuntos:	Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125894/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867519/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.5.909
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