Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Cyclic ADP-Ribose (cADPR) Mediate Ca2+ Signaling in Cardiac Hypertrophy Induced by β-Adrenergic Stimulation.

Ca2+ signaling plays a fundamental role in cardiac hypertrophic remodeling, but the underlying mechanisms remain poorly understood. We investigated the role of Ca2+-mobilizing second messengers, NAADP and cADPR, in the cardiac hypertrophy induced by β-adrenergic stimulation by isoproterenol. Isoprot...

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Ngā kaituhi matua:	Rukhsana Gul, Dae-Ryoung Park, Asif Iqbal Shawl, Soo-Yeul Im, Tae-Sik Nam, Sun-Hwa Lee, Jae-Ki Ko, Kyu Yoon Jang, Donghee Kim, Uh-Hyun Kim
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Public Library of Science (PLoS) 2016-01-01
Rangatū:	PLoS ONE
Urunga tuihono:	http://europepmc.org/articles/PMC4784992?pdf=render
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