Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB

Ser-133 phosphorylation of the cAMP-responsive element-binding protein (CREB) is sufficient to induce cellular gene expression in response to cAMP, but additional promoter-bound factors are required for target gene activation by CREB in response to mitogen/stress signals. To compare the relative eff...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mayr, Bernhard M., Canettieri, Gianluca, Montminy, Marc R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2001
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC58577/
https://ncbi.nlm.nih.gov/pubmed/11535812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191152098
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