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Computational Insight Into the Structural Organization of Full-Length Toll-Like Receptor 4 Dimer in a Model Phospholipid Bilayer

Toll-like receptors (TLRs) are a unique category of pattern recognition receptors that recognize distinct pathogenic components, often utilizing the same set of downstream adaptors. Specific molecular features of extracellular, transmembrane (TM), and cytoplasmic domains of TLRs are crucial for coor...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Patra, Mahesh Chandra, Kwon, Hyuk-Kwon, Batool, Maria, Choi, Sangdun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857566/
https://ncbi.nlm.nih.gov/pubmed/29593733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00489
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