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A Rational Insight into the Effect of Dimethyl Sulfoxide on TNF-α Activity

Direct inhibition of tumor necrosis factor-alpha (TNF-α) action is considered a promising way to prevent or treat TNF-α-associated diseases. The trimeric form of TNF-α binds to its receptor (TNFR) and activates the downstream signaling pathway. The interaction of TNF-α with molecular-grade dimethyl...

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Publicat a:Int J Mol Sci
Autors principals: Javaid, Nasir, Patra, Mahesh Chandra, Seo, Hana, Yasmeen, Farzana, Choi, Sangdun
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7763846/
https://ncbi.nlm.nih.gov/pubmed/33322533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249450
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