Can adjunctive therapies augment the efficacy of endovascular thrombolysis? A potential role for activated protein C

In the management of acute ischemic stroke, vessel recanalization correlates with functional status, mortality, cost, and other outcome measures. Thrombolysis with intravenous tissue plasminogen activator has many limitations that restrict its applicability, but recent advances in the development of...

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Veröffentlicht in:Neuropharmacology
Hauptverfasser: Amar, Arun Paul, Sagare, Abhay P., Zhao, Zhen, Wang, Yaoming, Nelson, Amy R., Griffin, John H., Zlokovic, Berislav V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857404/
https://ncbi.nlm.nih.gov/pubmed/28923278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2017.09.021
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