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Formulation, characterization, cytotoxicity and Salmonella/microsome mutagenicity (Ames) studies of a novel 5-fluorouracil derivative

5-Fluorouracil is one of the first line drugs for the systemic therapy of solid tumors like breast, colorectal, oesophageal, stomach, pancreatic, head and neck. It could be shown that sugars can improve the absorption across cell membranes and can help to bypass some pharmacokinetic problems. Carboh...

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Publicat a:Saudi Pharm J
Autors principals: Köksal Karayildirim, Çinel, Kotmakçi, Mustafa, Halay, Erkan, Ay, Kadir, Başpinar, Yücel
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856941/
https://ncbi.nlm.nih.gov/pubmed/29556128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2018.01.004
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