Formulation, characterization, cytotoxicity and Salmonella/microsome mutagenicity (Ames) studies of a novel 5-fluorouracil derivative

5-Fluorouracil is one of the first line drugs for the systemic therapy of solid tumors like breast, colorectal, oesophageal, stomach, pancreatic, head and neck.It could be shown that sugars can improve the absorption across cell membranes and can help to bypass some pharmacokinetic problems. Carbohy...

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Bibliografiska uppgifter
Huvudupphovsmän: Çinel Köksal Karayildirim, Mustafa Kotmakçi, Erkan Halay, Kadir Ay, Yücel Başpinar
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2018-03-01
Serie:Saudi Pharmaceutical Journal
Ämnen:
5-Fluorouracil
Micelles
Cytotoxicity
Genotoxicity
Ames test
Anti cancer activity
Länkar:http://www.sciencedirect.com/science/article/pii/S1319016418300045
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