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FYVE domain-containing protein ZFYVE28 regulates EGFR-signaling in podocytes but is not critical for the function of filtration barrier in mice

The kidney ultrafiltration barrier is formed of endothelial cells, the glomerular basement membrane and podocytes. Podocytes have a central role in normal physiology and disease pathogenesis of the glomerulus. Signaling through epidermal growth factor receptor (EGFR) in podocytes mediates developmen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zambrano, Sonia, Rodriguez, Patricia Q., Guo, Jing, Möller-Hackbarth, Katja, Schwarz, Angelina, Patrakka, Jaakko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856817/
https://ncbi.nlm.nih.gov/pubmed/29549365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23104-z
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