Expanded genomic profiling of circulating tumor cells in metastatic breast cancer patients to assess biomarker status and biology over time (CALGB 40502 and CALGB 40503, Alliance)

PURPOSE: We profiled circulating tumor cells (CTCs) to study the biology of blood-borne metastasis and to monitor biomarker status in metastatic breast cancer (MBC). METHODS: CTCs were isolated from 105 MBC patients using EPCAM-based immunomagnetic enrichment and fluorescence-activated cells sorting...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Magbanua, Mark Jesus M., Rugo, Hope S., Wolf, Denise M., Hauranieh, Louai, Roy, Ritu, Pendyala, Praveen, Sosa, Eduardo V., Scott, Janet H., Lee, Jin Sun, Pitcher, Brandelyn, Hyslop, Terry, Barry, William T., Isakoff, Steven J., Dickler, Maura, van’t Veer, Laura, Park, John W.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856614/
https://ncbi.nlm.nih.gov/pubmed/29311117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2312
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