Kinetic-Pharmacodynamic Model of Chemotherapy Induced Peripheral Neuropathy in Patients with Metastatic Breast Cancer Treated with Paclitaxel, Nab-Paclitaxel or Ixabepilone: CALGB 40502 (Alliance)

Chemotherapy induced peripheral neuropathy (CIPN) is a dose limiting toxicity caused by several chemotherapeutic agents. Currently, CIPN is managed by empirical dose modifications at the discretion of the treating physician. The goal of this research is to quantitate the dose-CIPN relationship to in...

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Bibliographic Details
Published in:AAPS J
Main Authors: Mehrotra, Shailly, Sharma, Manish R., Gray, Elizabeth, Wu, Kehua, Barry, William T., Hudis, Clifford, Winer, Eric P., Lyss, Alan P., Toppmeyer, Deborah L., Moreno-Aspitia, Alvaro, Lad, Thomas E., Valasco, Mario, Overmoyer, Beth, Rugo, Hope, Ratain, Mark J., Gobburu, Jogarao V.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711539/
https://ncbi.nlm.nih.gov/pubmed/28620884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-017-0101-9
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