Target identification and mechanism of action of picolinamide and benzamide chemotypes with antifungal properties

Invasive fungal infections are accompanied by high mortality rates that range up to 90%. At present, only three different compound classes are available for use in the clinic, and these often suffer from low bioavailability, toxicity and drug resistance. These issues emphasize an urgent need for nov...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Pries, Verena, Nöcker, Christina, Khan, Danish, Johnen, Philipp, Hong, Zebin, Tripathi, Ashutosh, Keller, Anna-Lena, Fitz, Michael, Perruccio, Francesca, Filipuzzi, Ireos, Thavam, Sasikala, Aust, Thomas, Riedl, Ralph, Ziegler, Slava, Bono, Fulvia, Schaaf, Gabriel, Bankaitis, Vytas, Waldmann, Herbert, Hoepfner, Dominic
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856591/
https://ncbi.nlm.nih.gov/pubmed/29307839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2017.12.007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados