Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane

The latent reservoir for HIV-1 in resting CD4(+) T cells is a major barrier to cure. Several lines of evidence suggest that the latent reservoir is maintained through cellular proliferation. Analysis of this proliferative process is complicated by the fact that most infected cells carry defective pr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Zheng, Gurule, Evelyn E., Brennan, Timothy P., Gerold, Jeffrey M., Kwon, Kyungyoon J., Hosmane, Nina N., Kumar, Mithra R., Beg, Subul A., Capoferri, Adam A., Ray, Stuart C., Ho, Ya-Chi, Hill, Alison L., Siliciano, Janet D., Siliciano, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856552/
https://ncbi.nlm.nih.gov/pubmed/29483265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720665115
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