Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane

The latent reservoir for HIV-1 in resting CD4(+) T cells is a major barrier to cure. Several lines of evidence suggest that the latent reservoir is maintained through cellular proliferation. Analysis of this proliferative process is complicated by the fact that most infected cells carry defective pr...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Wang, Zheng, Gurule, Evelyn E., Brennan, Timothy P., Gerold, Jeffrey M., Kwon, Kyungyoon J., Hosmane, Nina N., Kumar, Mithra R., Beg, Subul A., Capoferri, Adam A., Ray, Stuart C., Ho, Ya-Chi, Hill, Alison L., Siliciano, Janet D., Siliciano, Robert F.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856552/
https://ncbi.nlm.nih.gov/pubmed/29483265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720665115
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