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Human Ska complex and Ndc80 complex interact to form a load-bearing assembly that strengthens kinetochore–microtubule attachments

Accurate segregation of chromosomes relies on the force-bearing capabilities of the kinetochore to robustly attach chromosomes to dynamic microtubule tips. The human Ska complex and Ndc80 complex are outer-kinetochore components that bind microtubules and are required to fully stabilize kinetochore–...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Helgeson, Luke A., Zelter, Alex, Riffle, Michael, MacCoss, Michael J., Asbury, Charles L., Davis, Trisha N.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856539/
https://ncbi.nlm.nih.gov/pubmed/29487209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718553115
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