Grip and slip of L1-CAM on adhesive substrates direct growth cone haptotaxis

Chemical cues presented on the adhesive substrate direct cell migration, a process termed haptotaxis. To migrate, cells must generate traction forces upon the substrate. However, how cells probe substrate-bound cues and generate directional forces for migration remains unclear. Here, we show that th...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Abe, Kouki, Katsuno, Hiroko, Toriyama, Michinori, Baba, Kentarou, Mori, Tomoyuki, Hakoshima, Toshio, Kanemura, Yonehiro, Watanabe, Rikiya, Inagaki, Naoyuki
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2018
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5856512/
https://ncbi.nlm.nih.gov/pubmed/29483251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711667115
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