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Bayesian adaptive bandit-based designs using the Gittins index for multi-armed trials with normally distributed endpoints
Adaptive designs for multi-armed clinical trials have become increasingly popular recently because of their potential to shorten development times and to increase patient response. However, developing response-adaptive designs that offer patient-benefit while ensuring the resulting trial provides a...
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Publicado no: | J Appl Stat |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5856359/ https://ncbi.nlm.nih.gov/pubmed/29551849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02664763.2017.1342780 |
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