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Investigating stem cells in human colon by using methylation patterns

The stem cells that maintain human colon crypts are poorly characterized. To better determine stem cell numbers and how they divide, epigenetic patterns were used as cell fate markers. Methylation exhibits somatic inheritance and random changes that potentially record lifelong stem cell division his...

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Hlavní autoři: Yatabe, Yasushi, Tavaré, Simon, Shibata, Darryl
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC58561/
https://ncbi.nlm.nih.gov/pubmed/11517339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191225998
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