Leukadherin-1 ameliorates endothelial barrier damage mediated by neutrophils from critically ill patients

BACKGROUND: Multi-organ failure occurs during critical illness and is mediated in part by destructive neutrophil-to-endothelial interactions. The β2 integrin receptor, CR3 (complement receptor 3; Mac-1; CD11b/CD18), which binds endothelial intercellular adhesion molecule-1 (ICAM-1), plays a key role...

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Detalhes bibliográficos
Publicado no:J Intensive Care
Main Authors: Dickinson, Catherine M., LeBlanc, Brian W., Edhi, Muhammad M., Heffernan, Daithi S., Faridi, Mohd. Hafeez, Gupta, Vineet, Cioffi, William G., O’Brien, Xian, Reichner, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855997/
https://ncbi.nlm.nih.gov/pubmed/29568527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40560-018-0289-5
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