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Conservation, evolution, and regulation of splicing during prefrontal cortex development in humans, chimpanzees, and macaques

Changes in splicing are known to affect the function and regulation of genes. We analyzed splicing events that take place during the postnatal development of the prefrontal cortex in humans, chimpanzees, and rhesus macaques based on data obtained from 168 individuals. Our study revealed that among t...

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Détails bibliographiques
Publié dans:RNA
Auteurs principaux: Mazin, Pavel V., Jiang, Xi, Fu, Ning, Han, Dingding, Guo, Meng, Gelfand, Mikhail S., Khaitovich, Philipp
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855957/
https://ncbi.nlm.nih.gov/pubmed/29363555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.064931.117
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