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Conservation, evolution, and regulation of splicing during prefrontal cortex development in humans, chimpanzees, and macaques

Changes in splicing are known to affect the function and regulation of genes. We analyzed splicing events that take place during the postnatal development of the prefrontal cortex in humans, chimpanzees, and rhesus macaques based on data obtained from 168 individuals. Our study revealed that among t...

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Bibliographische Detailangaben
Veröffentlicht in:RNA
Hauptverfasser: Mazin, Pavel V., Jiang, Xi, Fu, Ning, Han, Dingding, Guo, Meng, Gelfand, Mikhail S., Khaitovich, Philipp
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855957/
https://ncbi.nlm.nih.gov/pubmed/29363555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.064931.117
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