Astroglial DJ-1 over-expression up-regulates proteins involved in redox regulation and is neuroprotective in vivo

DJ-1, a Parkinson's disease-associated protein, is strongly up-regulated in reactive astrocytes in Parkinson's disease. This is proposed to represent a neuronal protective response, although the mechanism has not yet been identified. We have generated a transgenic zebrafish line with incre...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Redox Biol
Main Authors: Frøyset, Ann Kristin, Edson, Amanda J., Gharbi, Naouel, Khan, Essa A., Dondorp, Daniel, Bai, Qing, Tiraboschi, Ettore, Suster, Maximiliano L., Connolly, Joanne B., Burton, Edward A., Fladmark, Kari E.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854894/
https://ncbi.nlm.nih.gov/pubmed/29525604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.02.010
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