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Comparative molecular field analysis and molecular dynamics studies of the dopamine D(2) receptor antagonists without a protonatable nitrogen atom

The dopaminergic hypothesis of schizophrenia is the main concept explaining the direct reasons of schizophrenia and the effectiveness of current antipsychotics. All antipsychotics present on the market are potent dopamine D(2) receptor antagonists or partial agonists. In this work we investigate a s...

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Bibliografske podrobnosti
izdano v:Med Chem Res
Main Authors: Kaczor, Agnieszka A., Żuk, Justyna, Matosiuk, Dariusz
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854747/
https://ncbi.nlm.nih.gov/pubmed/29576721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-018-2137-5
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