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Comparative molecular field analysis and molecular dynamics studies of the dopamine D(2) receptor antagonists without a protonatable nitrogen atom

The dopaminergic hypothesis of schizophrenia is the main concept explaining the direct reasons of schizophrenia and the effectiveness of current antipsychotics. All antipsychotics present on the market are potent dopamine D(2) receptor antagonists or partial agonists. In this work we investigate a s...

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Detalhes bibliográficos
Publicado no:Med Chem Res
Main Authors: Kaczor, Agnieszka A., Żuk, Justyna, Matosiuk, Dariusz
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854747/
https://ncbi.nlm.nih.gov/pubmed/29576721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-018-2137-5
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