Single- and two-photon imaging of human micrometastases and disseminated tumour cells with conjugates of nanobodies and quantum dots

Early detection of malignant tumours and, especially, micrometastases and disseminated tumour cells is still a challenge. In order to implement highly sensitive diagnostic tools we demonstrate the use of nanoprobes engineered from nanobodies (single-domain antibodies, sdAbs) and fluorescent quantum...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ramos-Gomes, Fernanda, Bode, Julia, Sukhanova, Alyona, Bozrova, Svetlana V., Saccomano, Mara, Mitkovski, Miso, Krueger, Julia Eva, Wege, Anja K., Stuehmer, Walter, Samokhvalov, Pavel S., Baty, Daniel, Chames, Patrick, Nabiev, Igor, Alves, Frauke
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854706/
https://ncbi.nlm.nih.gov/pubmed/29545609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22973-8
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