Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis

Regulatory T (Treg) cells contribute to the anti-inflammatory response during atherogenesis. Here we show that during atherogenesis Treg cells lose Foxp3 expression and their immunosuppressive function, leading to the conversion of a fraction of these cells into T follicular helper (Tfh) cells. We s...

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發表在:Nat Commun
Main Authors: Gaddis, Dalia E., Padgett, Lindsey E., Wu, Runpei, McSkimming, Chantel, Romines, Veronica, Taylor, Angela M., McNamara, Coleen A., Kronenberg, Mitchell, Crotty, Shane, Thomas, Michael J., Sorci-Thomas, Mary G., Hedrick, Catherine C.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854619/
https://ncbi.nlm.nih.gov/pubmed/29545616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03493-5
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