Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis

ATP-binding cassette transporter G1 (ABCG1) promotes cholesterol accumulation and alters T cell homeostasis, which may contribute to progression of atherosclerosis. Here, we investigated how the selective loss of ABCG1 in T cells impacts atherosclerosis in LDL receptor–deficient (LDLR-deficient) mic...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Cheng, Hsin-Yuan, Gaddis, Dalia E., Wu, Runpei, McSkimming, Chantel, Haynes, LaTeira D., Taylor, Angela M., McNamara, Coleen A., Sorci-Thomas, Mary, Hedrick, Catherine C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004951/
https://ncbi.nlm.nih.gov/pubmed/27482882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83136
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