On-target action of anti-tropomyosin drugs regulates glucose metabolism

The development of novel small molecule inhibitors of the cancer-associated tropomyosin 3.1 (Tpm3.1) provides the ability to examine the metabolic function of specific actin filament populations. We have determined the ability of these anti-Tpm (ATM) compounds to regulate glucose metabolism in mice....

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Kee, Anthony J., Chagan, Jayshan, Chan, Jeng Yie, Bryce, Nicole S., Lucas, Christine A., Zeng, Jun, Hook, Jeff, Treutlein, Herbert, Laybutt, D. Ross, Stehn, Justine R., Gunning, Peter W., Hardeman, Edna C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854615/
https://ncbi.nlm.nih.gov/pubmed/29545590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22946-x
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