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Secretome analysis of in vitro aged human mesenchymal stem cells reveals IGFBP7 as a putative factor for promoting osteogenesis

Aging is a complex biological process, which involves multiple mechanisms with different levels of regulation. Senescent cells are known to secrete senescence-associated proteins, which exert negative influences on surrounding cells. Mesenchymal stem cells (MSCs), the common progenitors for bone, ca...

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Pubblicato in:Sci Rep
Autori principali: Infante, Arantza, Rodríguez, Clara I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854613/
https://ncbi.nlm.nih.gov/pubmed/29545581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22855-z
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