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LPA signaling is regulated through the primary cilium: a novel target in glioblastoma

The primary cilium is a ubiquitous organelle presented on most human cells. It is a crucial signaling hub for multiple pathways including growth factor and G-protein coupled receptors. Loss of primary cilia, observed in various cancers, has been shown to affect cell proliferation. Primary cilia form...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Loskutov, Yuriy V., Griffin, Caryn L., Marinak, Kristina M., Bobko, Andrey, Margaryan, Naira V., Geldenhuys, Werner J., Sarkaria, Jann N., Pugacheva, Elena N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854509/
https://ncbi.nlm.nih.gov/pubmed/29321663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0049-3
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