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Diverse developmental programs of Xenopus laevis metamorphosis are inhibited by a dominant negative thyroid hormone receptor

Metamorphosis of anuran tadpoles is controlled by thyroid hormone (TH). Here we demonstrate that transgenic Xenopus laevis tadpoles expressing a dominant negative form of TH receptor-α are resistant to a wide variety of the metamorphic changes induced by TH. This result confirms that TH receptors me...

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Detalhes bibliográficos
Main Authors: Schreiber, Alexander M., Das, Biswajit, Huang, Haochu, Marsh-Armstrong, Nicholas, Brown, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC58545/
https://ncbi.nlm.nih.gov/pubmed/11517345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191361698
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