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Metamorphosis is inhibited in transgenic Xenopus laevis tadpoles that overexpress type III deiodinase

One of the genes that is up-regulated by thyroid hormone (TH) during Xenopus laevis metamorphosis encodes a type III deiodinase (D3) that inactivates TH. Transgenic X. laevis tadpoles overexpressing a GFP-D3 fusion protein were produced. These transgenic tadpoles had high levels of deiodinase activi...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Huang, Haochu, Marsh-Armstrong, Nicholas, Brown, Donald D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1999
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15333/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9927676/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.3.962
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