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Metamorphosis is inhibited in transgenic Xenopus laevis tadpoles that overexpress type III deiodinase

One of the genes that is up-regulated by thyroid hormone (TH) during Xenopus laevis metamorphosis encodes a type III deiodinase (D3) that inactivates TH. Transgenic X. laevis tadpoles overexpressing a GFP-D3 fusion protein were produced. These transgenic tadpoles had high levels of deiodinase activi...

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Main Authors: Huang, Haochu, Marsh-Armstrong, Nicholas, Brown, Donald D.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC15333/
https://ncbi.nlm.nih.gov/pubmed/9927676
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