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A Drosophila Model of Intellectual Disability Caused by Mutations in the Histone Demethylase KDM5
Mutations in KDM5 family histone demethylases cause intellectual disability in humans. However, the molecular mechanisms linking KDM5-regulated transcription and cognition remain unknown. Here, we establish Drosophila as a model to understand this connection by generating a fly strain harboring an a...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5854480/ https://ncbi.nlm.nih.gov/pubmed/29490272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.02.018 |
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