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Detecting Adaptation in Protein-Coding Genes Using a Bayesian Site-Heterogeneous Mutation-Selection Codon Substitution Model

Codon substitution models have traditionally attempted to uncover signatures of adaptation within protein-coding genes by contrasting the rates of synonymous and non-synonymous substitutions. Another modeling approach, known as the mutation–selection framework, attempts to explicitly account for sel...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Evol
Hauptverfasser: Rodrigue, Nicolas, Lartillot, Nicolas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854120/
https://ncbi.nlm.nih.gov/pubmed/27744408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msw220
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