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Mutation-selection models of coding sequence evolution with site-heterogeneous amino acid fitness profiles

Modeling the interplay between mutation and selection at the molecular level is key to evolutionary studies. To this end, codon-based evolutionary models have been proposed as pertinent means of studying long-range evolutionary patterns and are widely used. However, these approaches have not yet con...

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Detaylı Bibliyografya
Asıl Yazarlar: Rodrigue, Nicolas, Philippe, Hervé, Lartillot, Nicolas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842053/
https://ncbi.nlm.nih.gov/pubmed/20176949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910915107
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