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Mutation-selection models of coding sequence evolution with site-heterogeneous amino acid fitness profiles
Modeling the interplay between mutation and selection at the molecular level is key to evolutionary studies. To this end, codon-based evolutionary models have been proposed as pertinent means of studying long-range evolutionary patterns and are widely used. However, these approaches have not yet con...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2842053/ https://ncbi.nlm.nih.gov/pubmed/20176949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910915107 |
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