Hepatic Pharmacokinetics and Pharmacodynamics With Ombitasvir/Paritaprevir/Ritonavir Plus Dasabuvir Treatment and Variable Ribavirin Dosage

BACKGROUND: It is unknown whether ribavirin (RBV) coadministration modifies the early rate of decline of hepatitis C virus (HCV) RNA in the liver versus plasma compartments, specifically. METHODS: This partially randomized, open-label, phase 2 study enrolled treatment-naive, noncirrhotic patients wi...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Infect Dis
Autores principales: Talal, Andrew H, Dumas, Emily O, Bauer, Barbara, Rejman, Richard M, Ocque, Andrew, Morse, Gene D, Lucic, Danijela, Cloherty, Gavin A, King, Jennifer, Zha, Jiuhong, Zhang, Hongtao, Cohen, Daniel E, Shulman, Nancy, Pawlotsky, Jean-Michel, Hézode, Christophe
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
Major Articles and Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853515/
https://ncbi.nlm.nih.gov/pubmed/29228392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix495
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares