The Hemagglutinin A Stem Antibody MEDI8852 Prevents and Controls Disease and Limits Transmission of Pandemic Influenza Viruses

BACKGROUND: MEDI8852 is a novel monoclonal antibody (mAb) that neutralizes both group I and group II influenza A viruses (IAVs) in vitro. We evaluated whether MEDI8852 was effective for prophylaxis and therapy against representative group I (H5N1) and group II (H7N9) pandemic IAVs in mice and ferret...

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Publicado no:J Infect Dis
Main Authors: Paules, Catharine I, Lakdawala, Seema, McAuliffe, Josephine M, Paskel, Myeisha, Vogel, Leatrice, Kallewaard, Nicole L, Zhu, Qing, Subbarao, Kanta
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Major Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853468/
https://ncbi.nlm.nih.gov/pubmed/28633457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix292
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