Functional Analysis Reveals Geographical Variation in Inhibitory Immune Responses Against a Polymorphic Malaria Antigen

BACKGROUND: Plasmodium falciparum reticulocyte-binding protein homologue 2b (PfRh2b) is an invasion ligand that is a potential blood-stage vaccine candidate antigen; however, a naturally occurring deletion within an immunogenic domain is present at high frequencies in Africa and has been associated...

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Veröffentlicht in:J Infect Dis
Hauptverfasser: Bei, Amy K, Ahouidi, Ambroise D, Dvorin, Jeffrey D, Miura, Kazutoyo, Diouf, Ababacar, Ndiaye, Daouda, Premji, Zul, Diakite, Mahamadou, Mboup, Souleymane, Long, Carole A, Duraisingh, Manoj T
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Major Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853457/
https://ncbi.nlm.nih.gov/pubmed/28605544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix280
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