Single-Cell Tracking Reveals a Role for Pre-Existing CCR5(+) Memory Th1 Cells in the Control of Rhinovirus-A39 After Experimental Challenge in Humans

BACKGROUND: Little is known about T cells that respond to human rhinovirus in vivo, due to timing of infection, viral diversity, and complex T-cell specificities. We tracked circulating CD4(+) T cells with identical epitope specificities that responded to intranasal challenge with rhinovirus (RV)-A3...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Muehling, Lyndsey M, Turner, Ronald B, Brown, Kenneth B, Wright, Paul W, Patrie, James T, Lahtinen, Sampo J, Lehtinen, Markus J, Kwok, William W, Woodfolk, Judith A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853408/
https://ncbi.nlm.nih.gov/pubmed/29309618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix514
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