Circulating Memory CD4(+) T Cells Target Conserved Epitopes of Rhinovirus Capsid Proteins and Respond Rapidly to Experimental Infection in Humans

Rhinovirus (RV) is a major cause of common cold and an important trigger of acute episodes of chronic lung diseases. Antigenic variation across the numerous RV strains results in frequent infections and a lack of durable cross-protection. Since the nature of human CD4(+) T cells that target RV is la...

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Bibliographic Details
Published in:J Immunol
Main Authors: Muehling, Lyndsey M., Mai, Duy T., Kwok, William W., Heymann, Peter W., Pomés, Anna, Woodfolk, Judith A.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101128/
https://ncbi.nlm.nih.gov/pubmed/27591323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600663
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