Safety and Immunogenicity of Different Formulations of Norovirus Vaccine Candidate in Healthy Adults: A Randomized, Controlled, Double-Blind Clinical Trial

BACKGROUND: We investigated safety and immunogenicity of 1–2 doses of different bivalent virus-like particle (VLP) norovirus vaccine candidate (NoV) formulations in healthy 18- to 64-year-olds. METHODS: On days 1 and 28, participants (n = 420) randomized to 14 equal groups received intramuscular con...

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Библиографические подробности
Опубликовано в: :J Infect Dis
Главные авторы: Leroux-Roels, Geert, Cramer, Jakob P, Mendelman, Paul M, Sherwood, James, Clemens, Ralf, Aerssens, Annelies, De Coster, Ilse, Borkowski, Astrid, Baehner, Frank, Van Damme, Pierre
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
Предметы:
Major Articles and Brief Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853300/
https://ncbi.nlm.nih.gov/pubmed/29140444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jix572
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