Functional interleukin‐6 receptor‐α is located in tanycytes at the base of the third ventricle

Interleukin (IL)‐6(−)/(−) mice develop mature onset obesity, whereas i.c.v. injection of IL‐6 decreases obesity in rodents. Moreover, levels of IL‐6 in cerebrospinal fluid (CSF) were reported to be inversely correlated with obesity in humans. Tanycytes lining the base of the third ventricle (3V) in...

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Publicado en:J Neuroendocrinol
Autores principales: Anesten, F., Santos, C., Gidestrand, E., Schéle, E., Pálsdóttir, V., Swedung‐Wettervik, T., Meister, B., Patrycja Skibicka, K., Jansson, J.‐O.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852644/
https://ncbi.nlm.nih.gov/pubmed/29024103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jne.12546
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