Preproglucagon neurons in the hindbrain have IL-6 receptor-α and show Ca(2+) influx in response to IL-6

Neuronal circuits in the hypothalamus and hindbrain are of importance for control of food intake, energy expenditure, and fat mass. We have recently shown that treatment with exendin-4 (Ex-4), an analog of the proglucagon-derived molecule glucagon-like peptide 1 (GLP-1), markedly increases mRNA expr...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Anesten, Fredrik, Holt, Marie K., Schéle, Erik, Pálsdóttir, Vilborg, Reimann, Frank, Gribble, Fiona M., Safari, Cecilia, Skibicka, Karolina P., Trapp, Stefan, Jansson, John-Olov
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Obesity, Diabetes and Energy Homeostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967238/
https://ncbi.nlm.nih.gov/pubmed/27097661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00383.2015
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