BAG3 Overexpression and Cytoprotective Autophagy Mediate Apoptosis Resistance in Chemoresistant Breast Cancer Cells

Target-specific treatment modalities are currently not available for triple-negative breast cancer (TNBC), and acquired chemotherapy resistance is a primary obstacle for the treatment of these tumors. Here we employed derivatives of BT-549 and MDA-MB-468 TNBC cell lines that were adapted to grow in...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Das, Chandan Kanta, Linder, Benedikt, Bonn, Florian, Rothweiler, Florian, Dikic, Ivan, Michaelis, Martin, Cinatl, Jindrich, Mandal, Mahitosh, Kögel, Donat
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852393/
https://ncbi.nlm.nih.gov/pubmed/29462756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.01.001
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