Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction

Teneurins are ancient cell–cell adhesion receptors that are vital for brain development and synapse organisation. They originated in early metazoan evolution through a horizontal gene transfer event when a bacterial YD-repeat toxin fused to a eukaryotic receptor. We present X-ray crystallography and...

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Pubblicato in:Nat Commun
Autori principali: Jackson, Verity A., Meijer, Dimphna H., Carrasquero, Maria, van Bezouwen, Laura S., Lowe, Edward D., Kleanthous, Colin, Janssen, Bert J. C., Seiradake, Elena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851990/
https://ncbi.nlm.nih.gov/pubmed/29540701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03460-0
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